Department of Cell Biology

room no. C121
tel. no. (12) 664 6143
e-mail: jolanta.sroka@uj.edu.pl

Assistant professor

1993 – MSc
1999 – PhD
2010 – habilitation
degrees awarded by the Jagiellonian University

1. Department of Pathology, University of Bern, Switzerland,(1999-2000)
2. Department of Pathology, Karolinska Institute, Stockholm, Sweden, (2002, 2003)
3. 2001-2008 Secretary of the Krakow Branch of the Polish Society of Canadian Research
4. Prize of the Vice Chancellor of the Jagiellonian University for scientific achievements
5. 2005/2006 – grant of the Vice Chancellor Grant Fund of the Jagiellonian University
6. 2011 – prize of the Vice Chancellor of the Jagiellonian University for scientific achievements
7. Since 2011 – member of the Permanent Social Commission of the Vice Chancellor
8. Member of the auditing commission of the Krakow Branch of the Polish Society of Cell Biology (2011-2014)

• Research on the mechanisms of motility of healthy and malicious cells
• Impact of organic derivatives of heavy metals on cell migration and intercellular communication through gap junctional couplings
• Tioredoxin system in biological processes
• C protein kinase in control of cell motility
• Electrotaxis of healthy and malicious cells

Impact of toxic environmental factors on cells – (WBt-215)

1. Keller. H.U., Hunziker, I.P., Sordat, B., Niggli, V. and Sroka, J. (2000) Protein Kinase C isoforms involved in regulation of cell shape and locomotion of human fibrosarcoma HT1080 cells. Int. J. Cancer, 88, 195-203.
2. Sroka J., Madeja, M., Michalik, M., Przestalski, S and Korohoda W. (2002) Folic acid, ascorbic acid and sodium selenite restore the motility of Dictyostelium discoideum cells inhibited by trieethyllead. Toxicology, 180, 275-292.
3. Sroka J., Von Gunten M., Dunn G., and Keller H.U. (2002). Phenotype modulation in non-adherent and adherent sublines of Walker carcinosarcoma cells: the role cell-substratum contacts and microtubules in controlling cell shape, locomotion and cytoskeletal structure. Int. J. Biochem. Cell Biol., 1252, 1-18.
4. Madeja Z., Sroka J., Björkhem-Bergman L., Nyström C., Nordman T., Damdimopoulos A., Nalvarte I., Ericsson C., Spyrou G., Olsson Jm., Björnstedt M. (2005). The role of thioredoxin reductase activity in selenium induced cytotoxicity. Biochem. Pharmacol. 15; 69(12):1765-72.
5. Sroka J., Antosik A., Czyż J., Nalvarte I., Olsson J., Spyrou G, Madeja Z. (2007). Overexpression of thioredoxin reductase 1 inhibits migration of HEK-293 cells. Biol. Cell. 99: 677-687.
6. Sroka  J.,  Czyż J., Wojewoda M.,  Madeja Z. (2008). The inhibitory effect of diphenyltin on gap junctional intercellular communication in HEK-293 cells is reduced by thioredoxin reductase 1. Toxicol. Lett.  183: 45-51.
7. Sroka  J.,  Kordecka A., Włosiak P., Madeja Z., Korohoda W. (2009).  Separation Methods of PMNLs affects their motile activity. Eur. J. Cell. Biol. 88:531-9.
8. J. Sroka „Wpływ organicznych pochodnych cyny i ołowiu na migrację komórek zwierzęcych oraz międzykomórkową komunikację za pośrednictwem złącz szczelinowych" (2009) Seria Wydawnicza Wydziału Biochemii, Biofizyki i Biotechnologii Uniwersytetu Jagiellońskiego (rozprawa habilitacyjna).